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This third in a suite of four practical guides is an engineer's companion to using numerical methods for the solution of complex mathematical problems. It explains the theory behind current numerical methods and shows in a step-by-step fashion how to use them. The volume focuses on optimization from experimental to large-scale processes, detailing...

This issue of the Neurosurgery Clinics, Guest Edited by Drs. Jian, Ames, and Shaffrey, presents updates and state-of-the-art approaches to spinal deformity surgery. Spine surgery is a timely topics amongst neurosurgeons, and one that is continually evolving. Articles in this issue include Radiographic and Clinical Evaluation of Adult Spinal...

Educational Neuroscience presents a series of readings from educators, psychologists, and neuroscientists that explore the latest findings in developmental cognitive neurosciences and their potential applications to education. Represents a new research area with direct relevance to current educational practices and policy making Features...

Biological management of diseases of crops is influenced by the nature of interactions between the pathogens and other organisms and the plants. Due to development of resistance in pathogens to fungicides and bactericides, determination of compatibility of biotic biocontrol agents with chemicals is essential for selecting strains of biocontrol...

This first systematic treatment of the concept and practice of scaffold hopping shows the tricks of the trade and provides invaluable guidance for the reader's own projects. The first section serves as an introduction to the topic by describing the concept of scaffolds, their discovery, diversity and representation, and their importance for...

Edited by two renowned medicinal chemists who have pioneered the development of personalized therapies in their respective fields, this authoritative analysis of what is already possible is the first of its kind, and the only one to focus on drug development issues. Numerous case studies from the first generation of "personalized drugs" are...