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The 1980s: Ten-year-old Kate Meaney - with her 'Top Secret' notebook and Mickey her toy monkey - is busy being a junior detective. She observes goings-on and follows 'suspects' at the newly opened Green Oaks shopping centre and in her street, where she is friends with the newsagent's son, Adrian. But when this curious,...

A Surgeon's Notes on PerformanceThe struggle to perform well is universal, but nowhere is this drive to do better more important than in medicine. In his new book, Atul Gawande explores how doctors strive to close the gap between best intentions and best performance in the face of obstacles that sometimes seem insurmountable.His vivid stories...

DNA and the Revolution in Personalised MedicineWe are in the midst of a medical revolution: in just a few years, we will be able to have our complete DNA sequenced at an affordable cost. Analysing the content of our genomes will allow a powerful estimate of our future risks of illness - from cystic fibrosis and Huntington's disease, to cancer...

How To Get Things RightToday we find ourselves in possession of stupendous know-how, which we willingly place in the hands of the most highly skilled people. But avoidable failures are common, and the reason is simple: the volume and complexity of our knowledge has exceeded our ability to consistently deliver it - correctly, safely or efficiently....