Genetic Analysis - Philip Meneely

Genetic Analysis
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Autor: Philip Meneely

 Wydawnictwo: Oxford University Press
ISBN: 9780199651818
EAN:
Format: ...
Oprawa: miękka
Stron: 580
Data wydania: 2014-07-01
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How do we know what role a particular gene has? How do some genes control the expression of others? How do genes interact to form gene networks? With its unique integration of genetics and molecular biology, Genetic Analysis probes fascinating questions such as these, detailing how our understanding of key genetic phenomena can be used to understand biological systems. Opening with a brief overview of key genetic principles, model organisms, and epigenetics, the book goes on to explore the use of gene mutations and the analysis of gene expression and activity. A discussion of the genetic structure of natural populations follows, before the interaction of genes during suppression and epistasis, how we study gene networks, and personalized genomics are considered. Drawing on the latest experimental tools, including microarrays, RNAi screens, and bioinformatics approaches, Genetic Analysis provides a state-of-the-art review of the field, but in a truly student-friendly manner. It uses extended case studies and text boxes to augment the narrative, taking the reader right to the forefront of contemporary research, without losing clarity of explanation and insight. We are in an age where, despite knowing so much about biological systems, we are just beginning to realise how much more there is still to understand. Genetic Analysis is the ideal guide to how we can use the awesome power of molecular genetics to further our understanding. Online Resource Centre The Online Resource Centre to accompany Genetic Analysis features the following resources for teachers and students: For students: * Topical updates - key updates on topics or tools presented in the book, to keep you up-to-date with the latest developments in the field. * Additional case studies and text boxes to complement and add to those found in the book. * Practice problems, to test the reader's knowledge of the concepts presented, and help to master them. For registered adopters of the book: * Figures from the book in electronic format, ready to download. * Journal clubs - suggested papers and discussion questions linked to topics covered in the book. Review from previous edition It is, in many ways, the book I have been looking for since I started to teach this course 15 years ago: a book that teaches methods of genetic analysis and is suitable for a senior-level course. Dr Steve Mount, Department of Cell Biology and Molecular Genetics, University of Maryland, USA I love this text. I have not seen a text with as much current information on the most important aspects of genetics and genomics today. Professor Christine Rushlow, Department of Biology, New York University, USA It is an innovative effort to present standard genetic approaches in the context of recent genome-wide approaches. Professor Stephen H. Munroe, Biological Sciences, Marquette University, USA It is refreshing to see the focus move away from the detail of molecular mechanism towards understanding and scientific investigation. The Society for General Microbiology Philip Meneely makes a concerted effort to tie the key concepts derived from model systems to an understanding of human medical genetics, which works well and will be appreciated by students. The Society for General Microbiology.

Książka "Genetic Analysis"
Philip Meneely